Efektivitas Konseling Apoteker Terhadap Kepatuhan Pengobatan Pada Pasien Penyakit Paru Obstruktif Kronik: A Narative Review
DOI:
https://doi.org/10.59841/jumkes.v4i1.3566Keywords:
Edukasi Pasien, Inhaler, Kepatuhan Pengobatan, Konseling Apoteker, Penyakit Paru Obstruktif KronikAbstract
Penyakit Paru Obstruktif Kronik (PPOK) merupakan penyakit progresif yang ditandai oleh hambatan aliran udara yang tidak sepenuhnya reversibel, serta memiliki tingkat kepatuhan pengobatan yang rendah. Salah satu strategi yang dapat dilakukan untuk meningkatkan kepatuhan adalah melalui konseling oleh apoteker. Tujuan dari tinjauan literatur ini adalah untuk mengevaluasi pengaruh konseling apoteker terhadap tingkat kepatuhan pengobatan pada pasien PPOK. Pencarian data dilakukan melalui beberapa basis data, yaitu Google Scholar, Springer, ScienceDirect, dan PubMed dengan topik yang relevan. Hasil tinjauan menunjukkan bahwa konseling apoteker secara signifikan meningkatkan pemahaman pasien mengenai penyakit PPOK, manajemen eksaserbasi, dan teknik penggunaan inhaler yang benar. Selain itu, konseling juga berperan dalam mengurangi kecemasan, meningkatkan kepercayaan diri, efikasi diri, dan pengelolaan terapi yang lebih baik. Dengan demikian, implementasi konseling apoteker dalam praktik klinis sangat dianjurkan sebagai upaya meningkatkan kepatuhan pengobatan dan memperbaiki kualitas hidup pasien PPOK.
References
Abdulsalim, S., Unnikrishnan, M. K., Manu, M. K., Alrasheedy, A. A., Godman, B., & Morisky, D. E. (2018). Structured Pharmacist-led Intervention Programme to Improve Medication Adherence in COPD patients: A Randomized Controlled Study. Research in Social and Administrative Pharmacy, 14(10), 909–914. https://doi.org/10.1016/j.sapharm.2017.10.008
Adiana, I. N., & Putra, I. N. A. M. (2023). Hubungan Antara Tingkat Pendidikan Dan Komorbiditas Dengan Perilaku Perawatan Diri Pasien Penyakit Paru Obstruktif Kronis (PPOK). Jurnal Riset Kesehatan Nasional, 7(1), 72–77. https://doi.org/10.37294/jrkn.v7i1.486
Adisa, R., Ufuah, U. F., & Ige, O. M. (2024a). Impact of pharmacist-led intervention in medication adherence and inhaler usage on asthma and chronic obstructive pulmonary disease control: a quasi-experimental study. BMC Health Services Research, 24(1), 1199. https://doi.org/10.1186/s12913-024-11683-9
Adisa, R., Ufuah, U. F., & Ige, O. M. (2024b). Impact of pharmacist-led intervention in medication adherence and inhaler usage on asthma and chronic obstructive pulmonary disease control: a quasi-experimental study. BMC Health Services Research, 24(1), 1199. https://doi.org/10.1186/s12913-024-11683-9
Amelia, L., Oktobiannobel, J., Hasbie, N. F., & Soemarwoto, R. A. S. (2023). Gambaran Kepatuhan Penggunaan Inhaler Lama Dan Quality of Life Pada Pasien Ppok Di Kabupaten Pringsewu Provinsi Lampung. Jurnal Ilmu Kedokteran Dan Kesehatan, 10(5), 1943–1950. https://doi.org/10.33024/jikk.v10i5.10061
Bhattarai, A., Shakya, R., & Bista, D. (2024a). Impact of Pharmacist-Led Intervention on Adherence to Inhalers, Inhalation Technique, and Disease Control Among Asthma/COPD Patients in a Resource Limited Center: An Interventional Study. Patient Preference and Adherence , 18(June), 1395–1408. https://doi.org/10.2147/PPA.S460810
Bhattarai, A., Shakya, R., & Bista, D. (2024b). Impact of Pharmacist-Led Intervention on Adherence to Inhalers, Inhalation Technique, and Disease Control Among Asthma/COPD Patients in a Resource Limited Center: An Interventional Study. Patient Preference and Adherence , 18(June), 1395–1408. https://doi.org/10.2147/PPA.S460810
Ciptaningrum, I., & Karyus, A. (2022). Penatalaksanaan Holistik Pasien Tn. Lansia 65 Tahun Dengan Penyakit Paru Obstruktif Kronis Melalui Pendekatan Kedokteran Keluarga. Jurnal Kesehatan Tambusai, 3(1), 46–58.
Cohen, J., Rosenbaum, I., Oberman, B., Katz, I., Sharabi, N., & Shlomi, D. (2023). The impact of pharmacist-guided inhaler technique education on chronic obstructive pulmonary disease and asthma patients. Journal of Pharmaceutical Health Services Research, 14(2), 198–204. https://doi.org/10.1093/jphsr/rmad032
Ćulafić, M., Kovačević, M., Jovanović, M., Roganović, M., Vezmar Kovačević, S., Vučićević, K., & Miljković, B. (2023). Community pharmacist-driven interventions in COPD: improving knowledge, attitude and health status. Acta Poloniae Pharmaceutica - Drug Research, 79(5), 725–734. https://doi.org/10.32383/appdr/155353
Dhamane, A. D., Schwab, P., Hopson, S., Moretz, C., Annavarapu, S., Burslem, K., Renda, A., & Kaila, S. (2016). Association between adherence to medications for COPD and medications for other chronic conditions in COPD patients. International Journal of COPD, 12, 115–122. https://doi.org/10.2147/COPD.S114802
Ekaputri, M., & Ariani, Y. (2018). Upaya Berhenti Merokok Terhadap Peningkatan Perawatan Diri Pasien dengan Penyakit Paru Obstruktif Kronik (PPOK). Talenta Conference Series: Tropical Medicine (TM), 1(2), 387–390. https://doi.org/10.32734/tm.v1i2.221
Fitriarahmah, G., Peranginangin, J. M., & Keswara, Y. D. (2023). Hubungan Pelayanan Farmasi dengan Kepatuhan Pengobatan Pasien Penyakit Paru Obstruktif Kronik (PPOK). MPI (Media Pharmaceutica Indonesiana), 5(2), 146–155. https://doi.org/10.24123/mpi.v5i2.5808
GOLD. (2020). 2020 GOLD Reports- Pocket Guide To COPD Diagnosis,Management, and Prevention A Guide for Health Care Professionals. In Global Initiative for Chronic Obstructive Lung Disease, Inc.
GOLD. (2024). 2024 GLOLD Reports-Global Initiative for Chronic Obstructive Lung Disease. In The Lancet. Respiratory medicine (Vol. 12, Issue 1, pp. 15–16). https://doi.org/10.1016/S2213-2600(23)00461-7
Hanlon, P., Nicholl, B. I., Jani, B. D., McQueenie, R., Lee, D., Gallacher, K. I., & Mair, F. S. (2018). Examining patterns of multimorbidity, polypharmacy and risk of adverse drug reactions in chronic obstructive pulmonary disease: A cross-sectional UK Biobank study. BMJ Open, 8(1), 1–11. https://doi.org/10.1136/bmjopen-2017-018404
Herawati, A. T., Irawan, E., Lamonge, A. S., Wayunah, Sakti, B., & Wardhani, I. K. (2021). Buku Ajar Keperawatan Dewasa, Sistem Endoktrin, Imunologi, Pencernaan, Perkemihan dan Reproduksi Pria. CV. EUREKA MEDIKA AKSARA.
Huang, B., Willard-Grace, R., De Vore, D., Wolf, J., Chirinos, C., Tsao, S., Hessler, D., Su, G., & Thom, D. H. (2017). Health coaching to improve self-management and quality of life for low income patients with chronic obstructive pulmonary disease (COPD): Protocol for a randomized controlled trial. BMC Pulmonary Medicine, 17(1), 1–8. https://doi.org/10.1186/s12890-017-0433-3
Jacques, M. R., Kuhn, B. T., & Albertson, T. E. (2024). Update on the Pharmacological Treatment of Chronic Obstructive Pulmonary Diseade. Expert Opinion On Pharmacotherapy, 25(14), 1903–1922. https://doi.org/10.1080/14656566.2024.2409322
Khadela, A., Joshi, D., Vyas, B., & Patel, E. (2020). The Impact of Counseling in Patients with Chronic Obstructive Pulmonary Disease: Knowledge, Attitude, and Practice Outcome. Journal of Integrated Health Sciences, 8(2), 61. https://doi.org/10.4103/jihs.jihs_23_20
Kirana, S. S., Ramdini, D. A., Fitra, M., & Sayoeti, W. (2025). Faktor-Faktor yang Mempengaruhi Kepatuhan Pengobatan pada Pasien Penyakit Paru Obstruktif Kronik ( PPOK ) di Low and Middle Income Countries ( LMICs ): A Literature Review. Jurnal Riset Kesehatan Modern, 7(2), 200–211.
Klijn, S. L., Hiligsmann, M., Evers, S. M. A. A., Román-Rodríguez, M., Van Der Molen, T., & Van Boven, J. F. M. (2017). Effectiveness and Success Factors of Educational Inhaler Technique Interventions in Asthma & COPD Patients: A Systematic Review. Npj Primary Care Respiratory Medicine, 27(1), 1–10. https://doi.org/10.1038/s41533-017-0022-1
Lilyana, M. T. A. (2017). Manajemen Nonfarmakoterapi Bagi Pasien PPOK. Jurnal Ners Lentera, 5(2), 106–115.
Manisha, B., Aishwarya, B., Shekar, B., Mahesh, P., Adepu, R., & Sai Pawan, A. R. (2023). Influence of Pharmacist Counselling on Inhaler Usage Technique on Therapeutic Outcomes in Asthma and Chronic Obstructive Pulmonary Disease Patients. Indian Journal of Pharmaceutical Sciences, 85(4). https://doi.org/10.36468/pharmaceutical-sciences.1167
Marcelina, I., Samodra, G., & DM, P. O. (2023). Hubungan Kepatuhan Minum Obat Dengan Kualitas Hidup Pada Pasien Geriatri Penyakit Paru Obstruktif Kronik (Ppok) Di Rsud Banyumas. Journal of Nursing & Health, 7(3), 289–295.
Nguyen, T. S., Nguyen, T. L. H., Pham, T. T. Van, Hua, S., Ngo, Q. C., & Li, S. C. (2019). Impact of pharmaceutical care in the improvement of medication adherence and quality of life for COPD patients in Vietnam. Respiratory Medicine, 153, 31–37. https://doi.org/10.1016/j.rmed.2019.05.006
Nofrianti, A. S. U., Mardiana, M., & Irawati, I. (2023). Bagaimana Health Coaching Meningkatkan Self-efficacy Pasien Dengan Penyakit Pernafasan Kronis? Jurnal Promotif Preventif, 6(1), 66–74.
P, U., S, A., G, G. K., & P, M. (2020a). Impact of Patient Counseling on Health Knowledge and Medication Adherence in Asthma and Chronic Obstructive Pulmonary Disease Patients. Asian Journal of Pharmaceutical and Clinical Research, 13(5), 183–186. https://doi.org/10.22159/ajpcr.2020.v13i5.37324
P, U., S, A., G, G. K., & P, M. (2020b). Impact of Patient Counseling on Health Knowledge and Medication Adherence in Asthma and Chronic Obstructive Pulmonary Disease Patients. Asian Journal of Pharmaceutical and Clinical Research, 13(5), 183–186. https://doi.org/10.22159/ajpcr.2020.v13i5.37324
Park, S. K. (2017). Factors affecting self-care behavior in Koreans with COPD. Applied Nursing Research, 38(August 2016), 29–37. https://doi.org/10.1016/j.apnr.2017.09.003
Permenkes RI. (2016). Peraturan Mentri Kesehatan Republik Indonesia No. 72 Tahun 2016 Tentang Standar Pelayanan Kefarmasian Di Rumah Sakit.
PIR. (2015). Kedokteran Respirasi Untuk Dokter Layanan Primer. Universitas Sebelas Maret Press, 10–13.
Rabus, S. A., Yesilyaprak, G., & Izzettin, F. V. (2016). Drug-related problems and pharmacist interventions in a cohort of patients with asthma and chronic obstructive pulmonary disease. Respiratory Medicine, 120, 109–115. https://doi.org/10.1016/j.rmed.2016.10.006
Riset Kesehatan Dasar (RISKESDAS) 2013, Laporan Nasional 2013 1 (2013). https://doi.org/10.1126/science.127.3309.1275
Rodrigues, A. T., Romano, S., Romão, M., Figueira, D., Bulhosa, C., Madeira, A., Rocha, L., & Alves, J. (2021a). Effectiveness of a pharmacist-led intervention on inhalation technique for asthma and COPD patients: The INSPIRA pilot cluster-randomized controlled trial. Respiratory Medicine, 185(March). https://doi.org/10.1016/j.rmed.2021.106507
Rodrigues, A. T., Romano, S., Romão, M., Figueira, D., Bulhosa, C., Madeira, A., Rocha, L., & Alves, J. (2021b). Effectiveness of a pharmacist-led intervention on inhalation technique for asthma and COPD patients: The INSPIRA pilot cluster-randomized controlled trial. Respiratory Medicine, 185(March). https://doi.org/10.1016/j.rmed.2021.106507
Rodrigues, S. de O., da Cunha, C. M. C., Soares, G. M. V., Silva, P. L., Silva, A. R., & Gonçalves-De-albuquerque, C. F. (2021). Mechanisms, Pathophysiology and Currently Proposed Treatments of Chronic Obstructive Pulmonary Disease. Pharmaceuticals, 14(10). https://doi.org/10.3390/ph14100979
Sabiti, F. B., Fatiha, C. N., Timur, W. W., & Dewi, P. A. (2023). Pengaruh Konseling Apoteker Terhadap Kepatuhan Obat dan Nilai Tekanan Darah pada Pasien Hipertensi. Pharmacon : Jurnal Farmasi Indonesia, 20(2), 151–154.
Sari, C. P., Hanifah, S., Rosdiana, & Anisa, Y. (2021). Efektivitas Pengobatan pada Pasien Penyakit Paru Obstruksi Kronis (PPOK) di Rumah Sakit Wilayah Yogyakarta. Journal of Management and Pharmacy Practice, 11(4), 215. https://doi.org/10.22146/jmpf.56418
Suprobo, M. D., & Fadillah, N. (2020). Peran Konseling Apoteker Terhadap Pengetahuan Penggunaan Obat Dengan Sediaan Khusus Di Ketanggungan – Brebes. Jurnal Ilmu Farmasi Dan Farmasi Klinik, 17(01), 30. https://doi.org/10.31942/jiffk.v17i01.3504
Tamilselvan, T., Arya, A., Divya, N. M., Ananthu, N., Anjali, K. A., & Sailakshmi, S. (2022a). Pharmacist Care to Improve Medication Adherence and Quality Of Life of COPD Patients. Journal of Drug Delivery and Therapeutics, 12(3-S), 160–163. https://doi.org/10.22270/jddt.v12i3-s.5505
Tamilselvan, T., Arya, A., Divya, N. M., Ananthu, N., Anjali, K. A., & Sailakshmi, S. (2022b). Pharmacist Care to Improve Medication Adherence and Quality Of Life of COPD Patients. Journal of Drug Delivery and Therapeutics, 12(3-S), 160–163. https://doi.org/10.22270/jddt.v12i3-s.5505
West, K. (2023). Chronic Obstructive Pulmonary Disease Part 3: Inhaler Technique and Counseling Pearls. The Senior Care Pharmacist, 38(8), 311–314. https://doi.org/10.4140/TCP.n.2023.311
Widysanto, A., Goldin, J., & Mathew, G. (2025). Chronic Bronchitis. StatPearls Publishing.
Yulanda, N. A., & Mita. (2019). Pengaruh Modul Supportive Educative Terhadap Perawatan Diri Pasien Penyakit Paru Obstruktif Kronik. Journals of Ners Community, 10(2), 157–168.
Yusuf, Y., Pani, S., & Wirastuti, R. A. (2022). Analisis Drug Related Problem (DRP) Pengobatan PPOK Dengan Penyakit Penyerta Di RSUD Toto Kabila. Jurnal Ilmiah Dr. Aloei Saboe, 9(1), 1–11.
Zambelli-Simões, L., Martins, M. C., Possari, J. C. da C., Carvalho, G. B., Coelho, A. C. C., Cipriano, S. L., de Carvalho-Pinto, R. M., Cukier, A., & Stelmach, R. (2015). Validation of scores of use of inhalation devices: Valoration of errors. Jornal Brasileiro de Pneumologia, 41(4), 313–322. https://doi.org/10.1590/S1806-37132015000004435
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Jurnal Mahasiswa Ilmu Kesehatan
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
