Kegiatan Pengabdian dengan Edukasi dan Skrining Kolesterol dalam Rangka Pencegahan Penyakit Arteri Perifer pada Komunitas Dewasa di Kelurahan Krendang, Jakarta Barat

Authors

  • Alya Dwiana Universitas Tarumanagara
  • Alexander Halim Santoso Universitas Tarumanagara
  • Felix Felix Universitas Tarumanagara
  • Edwin Destra Universitas Tarumanagara
  • Fransisca Iriani Rosmala Dewi Universitas Tarumanagara

DOI:

https://doi.org/10.59841/jurai.v3i1.2219

Keywords:

Education, cholesterol, peripheral artery disease, prevention, screening

Abstract

Cholesterol is a type of fat naturally found in the body and plays a vital role in biological functions such as cell membrane formation and hormone production. However, elevated cholesterol levels can lead to plaque buildup in arterial walls, which is a major risk factor for peripheral artery disease. This condition is characterized by the narrowing of arteries that impedes blood flow, particularly to the extremities. A cholesterol screening program is conducted to detect elevated cholesterol levels early and to provide education about healthy lifestyle habits to adults. This program employs the Plan-Do-Check-Act (PDCA) approach, which includes planning, implementing education and screenings, evaluating effectiveness, and taking follow-up actions based on the results. The total cholesterol screenings revealed an average level of 181.81 with a standard deviation (SD) of 34.18. While this average is within the normal range, it approaches the upper limit, warranting caution to prevent further increases that could affect cardiovascular health in the future. Regular cholesterol screening can help minimize the risk of peripheral artery disease, thereby maintaining the quality of life for adults.

References

Chang, T.-Y., & Chen, J.-D. (2020). Low-Density Lipoprotein Cholesterol/Apolipoprotein B Ratio Is Superior to Apolipoprotein B Alone in the Diagnosis of Coronary Artery Calcification. Coronary Artery Disease, 32(6), 561–566. https://doi.org/10.1097/mca.0000000000001004

Colhoun, H. M., Leiter, L. A., Müller‐Wieland, D., Cariou, B., Ray, K. K., Tinahones, F. J., Domenger, C., Letierce, A., Israel, M., Samuel, R., & Prato, S. Del. (2020). Effect of Alirocumab on Individuals With Type 2 Diabetes, High Triglycerides, and Low High-Density Lipoprotein Cholesterol. Cardiovascular Diabetology, 19(1). https://doi.org/10.1186/s12933-020-0991-1

Durrington, P. N., Bashir, B., & Soran, H. (2022). What Should Be the Goal of Cholesterol-Lowering Treatment? A Quantitative Evaluation Dispelling Guideline Myths. Current Opinion in Lipidology, 33(4), 219–226. https://doi.org/10.1097/mol.0000000000000834

Gisterå, A., Klement, M. L., Polyzos, K. A., Mailer, R. K., Duhlin, A., Karlsson, M. C. I., Ketelhuth, D. F. J., & Hansson, G. K. (2018). Low-Density Lipoprotein-Reactive T Cells Regulate Plasma Cholesterol Levels and Development of Atherosclerosis in Humanized Hypercholesterolemic Mice. Circulation, 138(22), 2513–2526. https://doi.org/10.1161/circulationaha.118.034076

Grundy, S. M., Stone, N. J., Bailey, A. L., Beam, C., Birtcher, K. K., Blumenthal, R. S., Braun, L. T., Ferranti, S. D. de, Faiella-Tommasino, J., Forman, D. E., Goldberg, R., Heidenreich, P. A., Mark, D. B., Jones, D. W., Lloyd‐Jones, D. M., Lopez-Pajares, N., Ndumele, C. E., Orringer, C. E., Peralta, C. A., … Yeboah, J. (2019). 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation, 139(25). https://doi.org/10.1161/cir.0000000000000625

Hirano, T., Hirashima, T., Suzuki, N., Aoki, E., Hosoya, M., Oshima, T., Hayashi, T., Koba, S., Ohta, M., Satoh, N., & Ito, Y. (2022). Metabolic Properties of Lowdensity Lipoprotein (LDL) Triglycerides in Patients With Type 2 Diabetes, Comparison With Small Dense LDL-Cholesterol. Journal of Atherosclerosis and Thrombosis, 29(5), 762–774. https://doi.org/10.5551/jat.62789

Hirany, S. V, Dai, L., & Jialal, I. (1997). A More Valid Measurement of Low-Density Lipoprotein Cholesterol in Diabetic Patients. The American Journal of Medicine, 102(1), 48–53. https://doi.org/10.1016/s0002-9343(96)00375-0

Holewijn, S., Heijer, M. den, Swinkels, D. W., Stalenhoef, A. F. H., & Graaf, J. de. (2010). Apolipoprotein B, Non‐HDL Cholesterol and LDL Cholesterol for Identifying Individuals at Increased Cardiovascular Risk. Journal of Internal Medicine, 268(6), 567–577. https://doi.org/10.1111/j.1365-2796.2010.02277.x

Hwang, Y.-J., Ahn, H. Y., Park, S. W., & Park, C. (2014). Apolipoprotein B and Non-HDL Cholesterol Are More Powerful Predictors for Incident Type 2 Diabetes Than Fasting Glucose or Glycated Hemoglobin in Subjects With Normal Glucose Tolerance: A 3.3-year Retrospective Longitudinal Study. Acta Diabetologica, 51(6), 941–946. https://doi.org/10.1007/s00592-014-0587-x

Li, Y. H., Ueng, K. C., Jeng, J. S., Charng, M. J., Lin, T. H., Chien, K. L., Wang, C. Y., Chao, T. H., Liu, P. Y., Su, C. H., Chien, S. C., Liou, C. W., Tang, S. C., Lee, C. C., Yu, T. Y., Chen, J. W., Wu, C. C., & Yeh, H. I. (2017). 2017 Taiwan lipid guidelines for high risk patients. Journal of the Formosan Medical Association, 116(4), 217–248. https://doi.org/10.1016/j.jfma.2016.11.013

McHenry, S., Awad, A., Kozlitina, J., Stitziel, N. O., & Davidson, N. O. (2023). Low LDL Cholesterol Is Not an Independent Risk Factor for Hepatic Steatosis. Digestive Diseases and Sciences, 68(8), 3451–3457. https://doi.org/10.1007/s10620-023-07980-8

Nguyen, X. T., Ho, Y., Li, Y., Song, R. J., Leung, K. H., Rahman, S. U., Orkaby, A. R., Vassy, J. L., Gagnon, D. R., Cho, K., Gaziano, J. M., & Wilson, P. W. F. (2023). Serum Cholesterol and Impact of Age on Coronary Heart Disease Death in More Than 4 Million Veterans. Journal of the American Heart Association, 12(21). https://doi.org/10.1161/jaha.123.030496

Nurmohamed, N. S., Návar, A. M., & Kastelein, J. J. P. (2021). New and Emerging Therapies for Reduction of LDL-Cholesterol and Apolipoprotein B. Journal of the American College of Cardiology, 77(12), 1564–1575. https://doi.org/10.1016/j.jacc.2020.11.079

Pan-Lizcano, R., Mariñas-Pardo, L., Núñez, L., Rebollal, F., López-Vázquez, D., Pereira, A. B., Molina-Nieto, A., Calviño, R., Vázquez‐Rodríguez, J. M., & Hermida-Prieto, M. (2022). Rare Variants in Genes of the Cholesterol Pathway Are Present in 60% of Patients With Acute Myocardial Infarction. International Journal of Molecular Sciences, 23(24), 16127. https://doi.org/10.3390/ijms232416127

Paoli, A., Mancin, L., Giacona, M. C., Bianco, A., & Caprio, M. (2020). Effects of a ketogenic diet in overweight women with polycystic ovary syndrome. Journal of Translational Medicine, 18(1), 1–11. https://doi.org/10.1186/s12967-020-02277-0

Parhofer, K. G. (2022). New targets for treating hypertriglyceridemia. Current Opinion in Endocrinology, Diabetes and Obesity, 29(2), 106–111. https://doi.org/10.1097/MED.0000000000000714

Pham, K., Mulugeta, A., Lumsden, A. L., & Hyppönen, E. (2023). Genetically Instrumented LDL‐cholesterol Lowering and Multiple Disease Outcomes: A Mendelian Randomization Phenome‐wide Association Study in the UK Biobank. British Journal of Clinical Pharmacology, 89(10), 2992–3004. https://doi.org/10.1111/bcp.15793

Pischon, T., Girman, C. J., Sacks, F. M., Rifai, N., Stampfer, M. J., & Rimm, E. B. (2005). Non–High-Density Lipoprotein Cholesterol and Apolipoprotein B in the Prediction of Coronary Heart Disease in Men. Circulation, 112(22), 3375–3383. https://doi.org/10.1161/circulationaha.104.532499

Poznyak, A. V, Kashirskikh, D. A., Sukhorukov, V. N., Kalmykov, V., Omelchenko, A. V, & Orekhov, A. N. (2022). Cholesterol Transport Dysfunction and Its Involvement in Atherogenesis. International Journal of Molecular Sciences, 23(3), 1332. https://doi.org/10.3390/ijms23031332

Radyaputri, A. (2024). The Relationship of Apolipoprotein B and Major Adverse Cardiovascular Events (MACE) in Patients with Coronary Heart Disease as a Prognostic Factor: A Literature Review. SCRIPTA SCORE Scientific Medical Journal, 5(2), 165–170. https://doi.org/10.32734/scripta.v5i2.15234

Rajan, T., M, G., K, S., & L, E. (2024). Association Between Calculated Small Dense Low-Density Lipoprotein Cholesterol (sdLDL-C) and Soft Carotid Plaques on CT Angiogram of the Head and Neck. Cureus. https://doi.org/10.7759/cureus.65292

Ruslim, W. H., Santoso, A. H., Kurniawan, J., Destra, E., Setiawan, F. V., & Wijaya, B. A. (2024). Peningkatan Kewaspadaan terhadap Hiperlipidemia Melalui Pemeriksaan Kadar Kolesterol pada Kelompok Lanjut Usia di Panti Werda Hana. Jurnal Pelayanan Dan Pengabdian Masyarakat Indonesia, 3(2), 1–6.

Tang, F., Wang, J., Nicholas, S., Qian, D., & Liu, R. (2021). A Cohort Study on Risk Factors of High-Density Lipoprotein Cholesterol Hypolipidemia Among Urban Chinese Adults. Lipids in Health and Disease, 20(1). https://doi.org/10.1186/s12944-021-01449-1

Upadhyay, R. K. (2023). High Cholesterol Disorders, Myocardial Infarction and Its Therapeutics. World Journal of Cardiovascular Diseases, 13(08), 433–469. https://doi.org/10.4236/wjcd.2023.138040

Wang, Y., Zhao, X., Gao, H., Li, W., Wu, H., Wang, G., Liu, X., & Wu, S. (2023). The Impact of Accumulated Exposure to Non-High-Density Lipoprotein Cholesterol on Premature Cardiovascular Events. https://doi.org/10.21203/rs.3.rs-3388094/v1

Yang, H. S., Jeong, H. J., Kim, H., Lee, S., & Hur, M. (2023). Sex-Specific Relationships Between HDL-Cholesterol Levels and 10-Year Mortality in Individuals With Atherosclerotic Cardiovascular Disease: A Nationwide Cohort Study of South Koreans. Metabolites, 13(12), 1175. https://doi.org/10.3390/metabo13121175

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Published

2025-01-08

How to Cite

Alya Dwiana, Alexander Halim Santoso, Felix Felix, Edwin Destra, & Fransisca Iriani Rosmala Dewi. (2025). Kegiatan Pengabdian dengan Edukasi dan Skrining Kolesterol dalam Rangka Pencegahan Penyakit Arteri Perifer pada Komunitas Dewasa di Kelurahan Krendang, Jakarta Barat. Jurnal ABDIMAS Indonesia, 3(1), 19–27. https://doi.org/10.59841/jurai.v3i1.2219

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