Pengaruh Pemberian Ekstrak Etanol Daun Kunyit (Curcuma Domestica Val) Terhadap Kadar Glukosa Darah Tikus Putih (Rattus Norvegicus) Jantan Yang Di Induksi
DOI:
https://doi.org/10.59841/an-najat.v2i4.1682Keywords:
Turmeric Leaf (Curcuma Domestica Val), Diabetes Mellitus, Blood Glucose LevelsAbstract
Indonesia is the largest archipelago in the world (17,504 islands). In addition, Indonesia has abundant natural resources and fertile soil that allows a wide variety of plants to live. Curcuma domestica val, known as turmeric, is one of Indonesia's medicinal plants. A number of active ingredients found in turmeric have been shown in studies to have potential health benefits, including anti-diabetic anti-inflammatory, anti-cancer, cough medicine, liver medicine, and Alzheimer's disease. Based on the results of phytochemical research, flavonoids, alkaloids, tannins, triterpenoids, steroids, saponins, and glycosides are present in the ethyl ethanol extract of turmeric leaves (Curcuma domestica Val). Diabetes mellitus is a metabolic condition characterised by increased blood glucose levels caused by disruption of the insulin hormone which functions to lower blood glucose levels to maintain body homeostasis. Because of the close relationship between diabetes mellitus and lifestyle, diet, sleep, work, daily routine activities and others must be balanced. This study was conducted in the laboratory and was experimental in nature using male white rats as research subjects. Rats were induced using Alloxan at a dose of 100 mg/kgBB. Rats were divided into 6 groups, each consisting of 5 rats. Group 1 is a normal group, Group 2 is a negative group only given aquadest and induced with Alloxan.
References
Astutisari, I. D. A. E. C., Darmini, A. Y. D. A. Y., Ayu, I. A. P. W. I., & Wulandari, P. (2022). Hubungan Pola Makan Dan Aktivitas Fisik Dengan Kadar Gula Darah Pada Pasien Diabetes Melitus Tipe 2 Di Puskesmas Manggis I. Jurnal Riset Kesehatan Nasional, 6(2), 79-87.
Azhari, I. L., Rusmalirin, H., Suryanto, D., & Sihombing, D. R. (2018). Antimicrobial activity of turmeric leaf extract against Escherichia coli, Staphylococcus aureus, Shigella dysenteriae, and Lactobacillus acidophilus. IOP Conf. Ser.: Earth Environ. Sci. 205 (012048): 1-8.
Cahyana, Y., & Adiyanti, T. (2021). Flavonoid sebagai agen antidiabetik. Jurnal Kimia Indonesia , 21 (2), 512-526.
Carolia, N., & Fahryl, N. (2019). Kunyit (Curcuma domestica Val) sebagai Terapi artritis gout. Majority, 8(1), 251-255.
Edriana, N. (2014). Uji aktivitas antioksidan pada ekstrak daun Kunyit (Curcuma domestica val) dengan menggunakan metode DPPH (1,1-DIPHENYL-2-PICRYLHYDRAZYL). Skripsi, Universitas Islam Negeri Syarif Hidayatullah Jakarta.
Fauzy, A. (2020). Studi Etnobotani Tanaman Obat Di Wilayah Jawa Timur Dan Pemanfatannya Sebagai Media Edukasi Masyarakat Berbasis Website. Pedago Biologi: Jurnal Pendidikan dan Pembelajaran Biologi, 8(2), 46-52.
Komang, M. S. W. N., Putu, T. N. L., & Nengah, A. I. (2014). Studi pengaruh lamanya pemaparan medan magnet terhadap jumlah sel darah putih (leukosit) pada tikus putih (Rattus norvegicus). Buletin Fisika, 15(1), 31-38.
Mustofa, E. E., Purwono, J., & Ludiana, L. (2021). Penerapan Senam Kaki Terhadap Kadar Glukosa Darah Pada Pasien Diabetes Melitus Di Wilayah Kerja Puskesmas Purwosari Kec. Metro Utara Tahun 2021. Jurnal Cendikia Muda, 2(1), 78-86.
Siregar, R. S., Tanjung, A. F., Siregar, A. F., Salsabila, S., Bangun, I. H., & Mulya, M. O. (2021). Studi literatur tentang pemanfaatan tanaman obat tradisional. In Scenario (Seminar of Social Sciences Engineering and Humaniora) (pp. 385-391).
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 An-Najat
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.