Pola Penggunaan Antibiotik Pada Pasien Pneumonia Dewasa Rawat Inap RSU PKU Muhammadiyah Bantul Periode Tahun 2022
DOI:
https://doi.org/10.59841/an-najat.v2i1.663Keywords:
Pneumonia, Adults Patients, Patterns of Antibiotic UseAbstract
The prevalence of pneumoniae deaths in the world is around 2.56 million people in 2017. Based on the 2018 Riskesdas data, in Indonesia there has been an increase in the prevalence of pneumonia at all ages from 1.6% (2013) to 2.0% (2018). Pneumonia is an inflammation of the lungs that causes pain when breathing and limits oxygen intake. Pneumonia is caused by bacteria, viruses or mycoplasma. Antibiotics are the main drug in the management of infectious diseases. Adult patients are the groups most at risk for pneumoniae. Purpose: Knowing the pattern of antibiotic use in hospitalized adult pneumonia patients at RSU PKU Muhammadiyah Bantul for the 2022 period. This research is a non-experimental descriptive study. The sample used was 170 patients. Recording of patient data includes the patient's RM number, gender, age, drug given. Data were processed and analyzed descriptively, then calculated in percentage form and presented in tabular form. Results the research it showed the results of patients with an inpatient diagnosis of pneumonia dominated by men 59% and the elderly group 65%. The most widely used class of antibiotics were cephalosporin 36.65%, macrolide 33.22% and quinolones 22.95%. The most widely used antibiotic names were azithromycin 33.22%, ceftriaxone 23.63%, and levofloxacin 19.18%. The most common route of administration of antibiotics was the parenteral route 83% and the oral route 17% with the longest duration of administration of antibiotics for 3 days 47%, 5 days 36%, 7 days 12%, and 5% for administration of antibiotics > 7 days. Conclusion: Patients diagnosed with adult pneumoniae were dominated by 59% of men and 65% of the elderly group. The most widely used class of antibiotics was cephalosporins at 36.65%. The most widely used parenteral antibiotic was azithromycin at 33.22% with the longest duration of antibiotics being 3 days at 47%.
References
Arief, M. 1997. Ilmu Meracik Obat. Yogyakarta: Gadjah Mada Mada University Press.
Centers for Disease Control and Prevention (CDC). Pneumonia. (www.cdc.gov/pneumonia. diakses 29 Desember 2022).
Cilloniz C, Loeches I.M, Vidal C.G, Jose A.S. and Torres A. 2016. Microbial etiology of pneumonia: Epidemiology, diagnosis and resistance patterns. International Journal of Molecular Sciences, 17(12): 1-2.
Dewi, R., Sutrisno, D., & Pramirta, A. 2020. Evaluasi Penggunaan Antibiotik Pada Pasien Infeksi Saluran Pernafasan di Puskesmas Rawat Jalan Kecamatan Siulak Mukai Kabupaten Kerinci Tahun 2018. AsSyifaa Jurnal Farmasi, 12(3), 123– 130.
Elfidasari, D. Et Al., 2013. Deteksi Bakteri Klebsiella pneumonia Pada Beberapa Jenis Rokok Konsumsi Masyarakat., 2(1), Pp.41–47.
John E Stupka, Eric M Mortensen, Antonio Anzueto, et al. 2010. Community-acquired pneumonia in elderly patients, Published in final edited form as: Aging health. 2009; 5(6): 763–774: 20694055
Juwita, D.A.J., H. Arifin dan N. Yulianti. 2017. Kajian deskriptif retrospektif regimen dosis antibiotika pasien pneumonia anak di RSUP. Dr. M. Djamil Padang. Jurnal Sains Farmasi & Klinis. 3(2): 128-133.
Katzung, B. G. 2018. Basic & Clinical Pharmacology. 14th edn. Edited by B. G. Katzung. United States of America: McGraw-Hill Education
Kemenkes RI. 2021. Peraturan Menteri Kesehatan Republik Indonesia No. 28 Tahun 2021 Tentang Pedoman Penggunaan Antibiotik. Jakarta: Kemenkes RI. . 2018. Riset Kesehatan Dasar. Badan Penelitian Dan Pengembangan
Kesehatan Kemenkes RI, Jakarta (https://kesmas.kemkes.go.id/ diakses 27 Desember 2022). . 2013. Pedoman Tatalaksana Klinis Infeksi Saluran Pernapasan Akut Berat Suspek Middle East Respiratory Syndrome-Corona Virus (Mers- Cov). Jakarta:
Kemenkes RI.. 2011. Peraturan Menteri Kesehatan Republik Indonesia No. 2406 Tahun 2011 Tentang Pedoman Umum Penggunaan Antibiotik. Jakarta: Kemenkes RI.
Kirst, H. A. 2021. Azithromycin. In LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. Bethesda: National Institute of Diabetes and Digestive and Kidney Diseases
Mazumder, Shirin A. 2018. Practice of switch from intravenous to oral antibiotics. Springerplus. 2019; 3:717. Published online 2019:25674457
Notoatmojo, S. 2014. Metodologi Penelitian Kesehatan. Jakarta: Rineka Cipta.
Perhimpunan Dokter Paru Indonesia. 2014. Pedoman Diagnosis dan Penatalaksanaan Pneumonia Komuniti di Indonesia, Perhimpunan Dokter Paru Indonesia, Jakarta: Balai Penerbit FK UI.
Pingkan C, Heedy Tjirosantoso, Paulina V.Y. Yamlean. 2014. Evaluasi Kerasionalan Penggunaan Antibiotik Pada Pengobatan Pneumonia Anak Di Instalasi Rawat Inap RSUP Prof. Dr. R. D. Kandou Manado Periode Januari- Desember 2013. PHARMACON Vol. 3 No 3.
Rahmatullah, P. 2009. Penyakit Paru pada Usia Lanjut. Buku Ajar Geriatri (Ilmu Kesehatan Usia Lanjut). 4th ed. Jakarta: Balai Penerbit FKUI
Sugiyono. 206. Metode Penelitian Kuantitatif, Kualitatif danR&D. Bandung: PT Alfabet
Sunuwibirama 2019. Konsep Random Sampling Dalam Dunia Akademis. UGM. Yogyakarta.
Syamsudin dan Keban. 2013. Buku Ajar Farmakoterapi Gangguan Saluran Pernafasan. Jakarta: Salemba Medika.
Syarifuddin, N., & Natsir, S. 2019. Profil Penggunaan obat pada Pasien Penderita Infeksi Saluran Pernafasan Akut (ISPA) Di Puskesmas Empagae Kabupaten Sidenreng Rappang. Jurnal Ilmiah Kesehatan IQRA, 7(2), 58–63.
Triono, A.A dan Purwoko, A.E, 2012, Efektifitas Antibiotik Golongan Sefalosporin dan Kuinolon terhadap Infeksi Saluran Kemih, Mutiara Medika, 12(1): 6 -11
World Health Organization (WHO). 2016. Pneumonia, (http://www.who.int/mediacentre /factsheets/fs331 /en/ diakses 28 Desember 2022).
